@article { author = {Higashiyama, Shigeaki and Kawabe, Joji and Yoshida, Atsushi and Kotani, Kohei and Shiomi, Susumu}, title = {Usefulness of three-phase bone scintigraphy and SPECT/CT for the diagnosis of bone lesions of systemic sarcoidosis}, journal = {Asia Oceania Journal of Nuclear Medicine and Biology}, volume = {2}, number = {1}, pages = {69-72}, year = {2014}, publisher = {Mashhad University of Medical Sciences in collaboration with AOFNMB}, issn = {2322-5718}, eissn = {2322-5726}, doi = {10.7508/aojnmb.2014.01.010}, abstract = {We report a three-phase bone scintigraphy for the diagnosis of a peripheral bone lesion caused by systemic sarcoidosis. A 32-year-old man with suspected osteomyelitis of the right forefinger underwent three-phase bone scintigraphy with Tc-99m hydroxymethylene diphosphonate (HMDP) and single-photon emission computed tomography/computed tomography (SPECT/CT). The lesion was rich in blood flow according to flow study and blood pool study on bone scintigraphy, and was associated with an osteolytic change on SPECT/CT imaging performed 3 hours after injection of a radioisotope (RI). Whole-body bone scintigraphy indicated multiple high levels of abnormal RI accumulation. The findings of the three-phase bone scintigraphy and SPECT/CT suggested the presence of systemic sarcoidosis; however, a subsequent 18Ffluorodeoxyglucose positron emission tomography/CT (FDG-PET/CT) could not exclude the possibility of multiple metastases from testicular tumors. Therefore, testicular enucleation was performed, and the pathological examination confirmed the presence of sarcoidosis.}, keywords = {Sarcoidosis SPECT/CT Tc,99m HMDP Three,phase bone scintigraphy}, url = {https://aojnmb.mums.ac.ir/article_2220.html}, eprint = {https://aojnmb.mums.ac.ir/article_2220_3baf6a78e241e8391b9e32ccbebad894.pdf} }