@article { author = {Toriihara, Akira and Tsunoda, Atsunobu and Takemoto, Akira and Kubota, Kazunori and Machida, Youichi and Tateishi, Ukihide}, title = {Dual-time-point FDG-PET/CT Imaging of Temporal Bone Chondroblastoma: A Report of Two Cases}, journal = {Asia Oceania Journal of Nuclear Medicine and Biology}, volume = {3}, number = {2}, pages = {120-124}, year = {2015}, publisher = {Mashhad University of Medical Sciences in collaboration with AOFNMB}, issn = {2322-5718}, eissn = {2322-5726}, doi = {10.7508/aojnmb.2015.02.008}, abstract = {Temporal bone chondroblastoma is an extremely rare benign bone tumor. We encountered two cases showing similar imaging findings on computed tomography (CT), magnetic resonance imaging (MRI), and dual-time-point 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET)/CT. In both cases, CT images revealed temporal bone defects and sclerotic changes around the tumor. Most parts of the tumor showed low signal intensity on T2- weighted MRI images and non-uniform enhancement on gadolinium contrast-enhanced T1-weighted images. No increase in signal intensity was noted in diffusion-weighted images. Dual-time-point PET/CT showed markedly elevated 18F-FDG uptake, which increased from the early to delayed phase. Nevertheless, immunohistochemical analysis of the resected tumor tissue revealed weak expression of glucose transporter-1 and hexokinase II in both tumors. Temporal bone tumors, showing markedly elevated 18F-FDG uptake, which increases from the early to delayed phase on PET/CT images, may be diagnosed as malignant bone tumors. Therefore, the differential diagnosis should include chondroblastoma in combination with its characteristic findings on CT and MRI.  }, keywords = {temporal bone chondroblastoma,dual-time-point FDG-PET/CT,MRI}, url = {https://aojnmb.mums.ac.ir/article_3918.html}, eprint = {https://aojnmb.mums.ac.ir/article_3918_6a637697c253cec1cb9364810c1b06de.pdf} }