TY - JOUR ID - 11934 TI - A Rare Presentation of Colorectal Cancer with Unusual Progressive Intramuscular and Subcutaneous Metastatic Spread JO - Asia Oceania Journal of Nuclear Medicine and Biology JA - AOJNMB LA - en SN - 2322-5718 AU - Manafi-Farid, Reyhaneh AU - Ayati, Narjess AU - Eftekhari, Mohammad AU - Fallahi, Babak AU - Masoumi, Fardad AD - Research institute for Nuclear Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran AD - Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran AD - Research institute for Nuclear Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran. AD - Tabriz University of Medical Sciences, Tabriz, Iran Y1 - 2019 PY - 2019 VL - 7 IS - 1 SP - 89 EP - 94 KW - Colorectal carcinoma KW - Muscle metastasis KW - Rare metastasis KW - 18F-fluorodeoxyglucose PET/CT DO - 10.22038/aojnmb.2018.11934 N2 - Colorectal carcinoma is one of the most common causes of cancer-related death, worldwide. Recently, due to the introduction of novel imaging and therapeutic techniques, five-year survival of patients has increased. However, distant metastasis is still expected in half of the patients. Colorectal cancer tends to target the abdominal cavity, liver, lungs, and bones as the common sites of metastasis. Nevertheless, rare cases of muscle metastasis have been reported. This report presents a 23-year-old male, who despite chemotherapy, demonstrated gradual progressive disease and metastases to the submandibular region, lungs, adrenal gland as well as muscles and subcutaneous tissues. He had developed multiple asymptomatic muscular metastases metachronously over two-year time period discovered on an 18FDGPET/CT, namely in the deltoid, external oblique abdominis, rectus abdominis, and quadriceps muscles, as well as one of the extrinsic muscles of the tongue. The presence of distant, especially extrahepatic metastasis, adversely affects the prognosis of colon carcinoma. Since limited cases of muscle metastasis have been reported in carcinoma of colon, the underlying pathophysiology, optimum treatment, and prognostic issues are yet to be substantiated. UR - https://aojnmb.mums.ac.ir/article_11934.html L1 - https://aojnmb.mums.ac.ir/article_11934_34ecaaf216261e92101d53282254e56a.pdf ER -