TY - JOUR ID - 3918 TI - Dual-time-point FDG-PET/CT Imaging of Temporal Bone Chondroblastoma: A Report of Two Cases JO - Asia Oceania Journal of Nuclear Medicine and Biology JA - AOJNMB LA - en SN - 2322-5718 AU - Toriihara, Akira AU - Tsunoda, Atsunobu AU - Takemoto, Akira AU - Kubota, Kazunori AU - Machida, Youichi AU - Tateishi, Ukihide AD - Department of Diagnostic Radiology and Nuclear Medicine, Tokyo Medical and Dental University, Yushima, Bunkyoku, Tokyo, Japan AD - Department of Otolaryngology, Tokyo Medical and Dental University, Yushima, Bunkyo-ku, Tokyo, Japan AD - Department of Human Pathology, Tokyo Medical and Dental University, Yushima, Bunkyo-ku, Tokyo, Japan Y1 - 2015 PY - 2015 VL - 3 IS - 2 SP - 120 EP - 124 KW - temporal bone chondroblastoma KW - dual-time-point FDG-PET/CT KW - MRI DO - 10.7508/aojnmb.2015.02.008 N2 - Temporal bone chondroblastoma is an extremely rare benign bone tumor. We encountered two cases showing similar imaging findings on computed tomography (CT), magnetic resonance imaging (MRI), and dual-time-point 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET)/CT. In both cases, CT images revealed temporal bone defects and sclerotic changes around the tumor. Most parts of the tumor showed low signal intensity on T2- weighted MRI images and non-uniform enhancement on gadolinium contrast-enhanced T1-weighted images. No increase in signal intensity was noted in diffusion-weighted images. Dual-time-point PET/CT showed markedly elevated 18F-FDG uptake, which increased from the early to delayed phase. Nevertheless, immunohistochemical analysis of the resected tumor tissue revealed weak expression of glucose transporter-1 and hexokinase II in both tumors. Temporal bone tumors, showing markedly elevated 18F-FDG uptake, which increases from the early to delayed phase on PET/CT images, may be diagnosed as malignant bone tumors. Therefore, the differential diagnosis should include chondroblastoma in combination with its characteristic findings on CT and MRI.   UR - https://aojnmb.mums.ac.ir/article_3918.html L1 - https://aojnmb.mums.ac.ir/article_3918_6a637697c253cec1cb9364810c1b06de.pdf ER -