Extra-striatal Uptake of 99mTc-TRODAT SPECT in a Cerebral Meningioma: A Case Report

Document Type : Case report

Authors

1 Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

2 Department of Neurology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

3 Nuclear Medicine Research Center, Ghaem Hospital,Mashhad,Iran

Abstract

We reported a 71 years old woman, with history of rest and postural tremor, bradykinesia and memory problems. In her dynamic MRI, a contrastenhanced tumor in the cerebellopontine (CP) angle was found which was compatible with a meningioma. 99mTc-TRODAT SPECT showed decreased activity in the left putamen, indicating idiopathic Parkinson disease. There was also a focus of increased activity on the right side of the skull base, which was compatible with meningioma in MRI.

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1. Sasannezhad P, Juibary AG, Sadri K, Sadeghi R, Sabour M, Kakhki VRD, et al. (99m)Tc-TRODAT-1 SPECT imaging in early and late onset Parkinson’s disease. Asia Ocean J Nucl Med Biol. 2017;5(2):114-9.
2. Fallahi B, Esmaeili A, Beiki D, Oveisgharan S, Noorollahi-Moghaddam H, Erfani M, et al. Evaluation of (99m)Tc-TRODAT-1 SPECT in the diagnosis of Parkinson’s disease versus other progressive movement disorders. Ann Nucl Med. 2016;30(2):153-62.
3. Benincasa D, Romano A, Mastronardi L, Pellicano C, Bozzao A, Pontieri FE. Hemiparkinsonism due to frontal meningioma. Acta Neurol Belg. 2008;108(1):29-32.
4. Bor-Seng-Shu E, Pedroso JL, Felicio AC, de Andrade DC, Teixeira MJ, Braga-Neto P, et al. Substantia nigra echogenicity and imaging of striatal dopamine transporters in Parkinson’s disease: a cross-sectional study. Parkinsonism Relat Disord. 2014;20(5):477-81.
5. Adhiyaman V, Meara J. Meningioma presenting as bilateral parkinsonism. Age Ageing. 2003;32(4):456-8.
6. Watts J, Box G, Galvin A, Brotchie P, Trost N, Sutherland T. Magnetic resonance imaging of meningiomas: a pictorial review. Insights Imaging. 2014;5(1):113-22.
7. Saloner D, Uzelac A, Hetts S, Martin A, Dillon W. Modern meningioma imaging techniques. J Neurooncol. 2010;99(3):333-40.
8. Bor-Seng-Shu E, Felicio AC, Braga-Neto P, Batista IR, Paiva WS, de Andrade DC, et al. Dopamine transporter imaging using 99mTc-TRODAT-1 SPECT in Parkinson’s disease. Med Sci Monit. 2014;20:1413-8.
9. Chandra P, Nath S. Extra-striatal uptake of (99m)TcTRODAT-1 in meningioma detected on SPECT/CT: diagnostic clue or mere coincidence? Indian J Nucl Med. 2017;32(3):243-4.
10. Hwang WJ, Yao WJ, Wey SP, Ting G. Reproducibility of 99mTc-TRODAT-1 SPECT measurement of dopamine transporters in Parkinson’s disease. J Nucl Med. 2004;45(2):207-13.
11. Chiu YL, Hu C, Li JY, Weng MJ, Lin WC, Peng NJ. An incidental finding of cerebral meningioma on 99mTc-TRODAT-1 dopamine transporter SPECT/CT. Clin Nucl Med. 2012;37(9):899-900.
12. Vitor T, Carvalho GC, Nogueira SA, Wagner J, Felicio AC. Incidental detection of probable meningioma in brain scintigraphy using 99mTc-TRODAT-1. Arq Neuropsiquiatr. 2017;75(4):258-9.