@article { author = {Mohamedkhair, Ali and Al-ibraheem, Akram and Abdlkadir, Ahmed and Jaber, Omar}, title = {Challenging Results on FDG PET/CT in a Patient with Uncontrolled Celiac Disease and small bowel adenocarcinoma}, journal = {Asia Oceania Journal of Nuclear Medicine and Biology}, volume = {10}, number = {2}, pages = {155-160}, year = {2022}, publisher = {Mashhad University of Medical Sciences in collaboration with AOFNMB}, issn = {2322-5718}, eissn = {2322-5726}, doi = {10.22038/aojnmb.2022.61853.1437}, abstract = {Celiac disease (CD) is a chronic immune-mediated enteropathy that is caused by both environmental (gluten) and genetic (human leukocyte antigen (HLA) and non-HLA genes) factors. Patients may be asymptomatic or exhibit atypical symptoms, necessitating a high index of suspicion for proper diagnosis.The evaluation of CD patients with 18F-FDG PET/CT imaging can be difficult, owing to the fact that this disease is inflammatory in nature. Typical 18F-FDG PET/CT gastrointestinal manifestations of celiac disease include increased multifocal or diffuse bowel uptake, whereas single short segmental uptake is rarely encountered; thus, awareness of this wide range of findings is important to guide physicians through proper management and outcome.We report a case of small intestine adenocarcinoma and known CD complaining of recent episodes of diarrhea and weight loss that had a suspicious small bowel wall thickening that corresponds to a short segmental hypermetabolic process on FDG PET/CT follow-up scan. The patient was then referred to the gastroenterology department and underwent a colonoscopy, a biopsy was taken that revealed CD and was negative for malignancy. Furthermore, 6 months later the abovementioned segmental FDG activity was completely resolved without any treatment received at the given time.}, keywords = {Celiac disease,FDG PET/CT,Single Short Segmental Bowel Uptake,Adenocarcinoma}, url = {https://aojnmb.mums.ac.ir/article_19621.html}, eprint = {https://aojnmb.mums.ac.ir/article_19621_5e0da59ec446da3719f59d81b9ec42e6.pdf} }