@article { author = {Toriihara, Akira and Nakadate, Masashi and Nakamura, Shin and Kubota, Kazunori and Tateishi, Ukihide}, title = {Seventy FDG-PET/CT cases in which nuclear medicine physicians suspected lymphoma: How reliable are we?}, journal = {Asia Oceania Journal of Nuclear Medicine and Biology}, volume = {5}, number = {2}, pages = {97-106}, year = {2017}, publisher = {Mashhad University of Medical Sciences in collaboration with AOFNMB}, issn = {2322-5718}, eissn = {2322-5726}, doi = {10.22038/aojnmb.2017.8767}, abstract = {Objective(s): To validate the reliability of nuclear medicine physicians in diagnosing lymphoma using positron emission tomography/computed tomography using 2-deoxy-2-[18F]fluoro-D-glucose (FDG-PET/CT) and to determine findings that reliably suggest lymphoma.Methods: Seventy patients suspected of having lymphoma using FDG-PET/CT were enrolled in this retrospective study. Two nuclear medicine physicians read all the interpretation reports and graded the degree of suspicion by consensus (3: definitely suspicious, 2: probably suspicious, and 1: possibly suspicious). The following factors were also investigated for each patient: maximum standardized uptake value (SUVmax) of the lesions, serum level of soluble interleukin-2 receptor (sIL-2R), and the presence of splenic FDG uptake higher than that of the liver.Results: The study group consisted of 34 lymphomas, 18 other malignancies, and 18 benign lesions according to histopathological diagnosis. No patient with a Grade 1 degree of suspicion was diagnosed as lymphoma. SUVmax and the serum level of sIL2-R could not distinguish lymphoma from other diseases. Of the 11 patients who presented with elevated splenic FDG uptake, 10 were diagnosed as having lymphoma.Conclusion: When the degree of suspicion by nuclear medicine physicians is low, the possibility of lymphoma is also low. On the other hand, elevated splenic FDG uptake may suggest lymphoma. }, keywords = {Lymphoma,FDG-PET/CT,SUVmax,soluble interleukin-2 receptor,Spleen}, url = {https://aojnmb.mums.ac.ir/article_8767.html}, eprint = {https://aojnmb.mums.ac.ir/article_8767_b9174c7e7609b6acbfdbe43404cd70c3.pdf} }