TY - JOUR ID - 10183 TI - Utility of 99mTc-Sestamibi SPECT/CT in the Early Localization of Metastatic Parathyroid Carcinoma JO - Asia Oceania Journal of Nuclear Medicine and Biology JA - AOJNMB LA - en SN - 2322-5718 AU - Fernando, Patrick Earl Amparado AU - Bautista, Patricia Amado AD - Department of Nuclear Medicine and PET Center St. Luke's Medical Center Bonifacio Global City, Taguig, Philippines Y1 - 2018 PY - 2018 VL - 6 IS - 2 SP - 171 EP - 178 KW - Parathyroid carcinoma KW - SPECT/CT KW - 99mTc-sestamibi DO - 10.22038/aojnmb.2017.27484.1190 N2 - Parathyroid carcinoma is very rare, with only a few documented cases. Hence, metastatic lesions are infrequently documented on scintigraphic imaging. We present a case of a 63-year-old female presenting with elevated serum levels of ionized calcium and parathyroid hormone (PTH) who was referred to our department for a parathyroid scan with SPECT/ CT. Parathyroid scintigraphy showed a focus of increased 99mTc-sestamibi uptake corresponding to a solid mass with calcification in the inferior pole of the right thyroid lobe; tracer retention was noted on delayed images. Incidentally, focal uptake was also seen in a soft tissue mass on the 7th right rib. The patient soon underwent total thyroidectomy, with biopsy revealing parathyroid carcinoma on the right lobe. A bone scan done 7 months after surgery confirmed the presence of metastatic bone disease. The concomitant detection of intrathyroidal and extrathyroidal sestamibiavid masses on parathyroid scintigraphy should increase clinical suspicion of a metastatic process from parathyroid carcinoma. UR - https://aojnmb.mums.ac.ir/article_10183.html L1 - https://aojnmb.mums.ac.ir/article_10183_00a21d1ee413ff4349db1d29f0e6748e.pdf ER -