TY - JOUR ID - 16522 TI - Physiological FDG uptake in growth plate on pediatric PET JO - Asia Oceania Journal of Nuclear Medicine and Biology JA - AOJNMB LA - en SN - 2322-5718 AU - Otani, Tomoaki AU - Nakamoto, Yuji AU - Ishimori, Takayoshi AD - Department of Diagnostic Imaging and Nuclear Medicine, Graduate School of Medicine, Kyoto University, Japan Y1 - 2021 PY - 2021 VL - 9 IS - 1 SP - 15 EP - 20 KW - Growth plate KW - physiological FDG uptake KW - FDG DO - 10.22038/aojnmb.2020.49638.1339 N2 - Objective(s):18F-Fluorodeoxyglucose (FDG) uptake in children is different from that in adults. Physiological accumulation is known to occur in growth plates, but the pattern of distribution has not been fully investigated. Our aim was to evaluate the metabolic activity of growth plates according to age and location. Methods:We retrospectively evaluated 89 PET/CT scans in 63 pediatric patients (male : female=25 : 38, range, 0–18 years). Patients were classified into four age groups (Group A: 0–2 years, Group B: 3–9 years, Group C: 10–14 years and Group D: 15-18 years). The maximum standardized uptake value (SUVmax) of the proximal and distal growth plates of the humerus, the forearm bones and the femur were measured. The SUVmax of each site and each age group were compared and statistically analyzed. We also examined the correlations between age and SUVmax. Results:As for the comparison of SUVmax in each location, the SUVmax was significantly higher in the distal femur than those in the other sites (p< 0.01). SUVmax in the distal humerus and the proximal forearm bones were significantly lower than those in the other sites (p< 0.01). In the distal femur, there was large variation in SUVmax, while in the distal humerus and the proximal forearm bones, there was small variation. As for the comparison of SUVmax in each age group, the SUVmax in group D tended to be lower than those in the other groups, but in the distal femur, there was no significant difference among each age group. Conclusion:Our data indicate that FDG uptake in growth plates varies depending on the site and age with remarkable uptake especially in the distal femur. UR - https://aojnmb.mums.ac.ir/article_16522.html L1 - https://aojnmb.mums.ac.ir/article_16522_8f7b0ee422e130ad2aacc9013a7a7857.pdf ER -