Incidental Detection of Left Ventricular Metastasis from Lung Squamous Cell Carcinoma on FDG PET/CT: A Rare Case Report

Articles in Press

Document Type : Case report

Authors

1 Nuclear Medicine Dept. King Hussein Cancer Center, Amman, Jordan

2 Nuclear Medicine Dept, King Hussein Cancer Center, Amman, Jordan

3 King Hussain cancer center

10.22038/aojnmb.2026.92391.1682

Abstract

Cardiac metastases are uncommon, particularly in the left ventricle, where lesions often remain asymptomatic and can be easily overlooked on conventional imaging. Lung cancer, a leading cause of global cancer-related morbidity and mortality, accounts for approximately one-third of all cases of cardiac metastases among various malignancies. We present a 62-year-old male with stage IV squamous cell carcinoma of the lung, who exhibited widespread systemic metastases. Staging Fluorine-18 Fluorodeoxyglucose (¹⁸F-FDG) Positron Emission Tomography/Computed Tomography (PET/CT) revealed a hypermetabolic cavitary left upper lobe mass with a metastatic process involving multiple nodal, adrenal, hepatic, osseous, and cerebral deposits, along with an incidental focal FDG-avid lesion in the left ventricle that was not detected on initial CT. Echocardiography confirmed preserved cardiac function with a normal ejection fraction. Given uncommon nature of left ventricular involvement by squamous cell carcinoma and the limited number of similar reported cases, our findings contribute to the growing evidence supporting the critical role of ¹⁸F-FDG PET/CT in detecting clinically silent occult cardiac metastasis.

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Asia Oceania Journal of Nuclear Medicine and Biology

Articles in Press, Accepted Manuscript
Available Online from 28 April 2026

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