Asia Oceania Journal of Nuclear Medicine and Biology

Asia Oceania Journal of Nuclear Medicine and Biology

Bone scintigraphy in staging of newly diagnosed prostate cancer in regard of different risk groups

Document Type : Short communication

Authors
Sabina Sevcenco 1
Bernhard Grubmuller 2
Charlotte Sonneck-Koenne 3
Yasaman Ahmadi 3
Peter Knoll 3
Andreas Floth 4
Wolfgang Pokieser 5
Shahin Zandieh 6
Hans-Christoph Klingler 4
Shahrokh Shariat 2
Siroos Mirzaei 3
1 1Department of Urology, SMZ Ost, Donauspital, Vienna
2 Department of Urology, University of Vienna
3 Department of Nuclear Medicine with PET-Center, Wilhelminenspital, Vienna
4 Department of Urology, Wilhelminenspital, Vienna
5 Department of Pathology, Wilhelminenspital, Vienna
6 Institute of Radiology and Nuclear Medicine, Hanusch Hospital, Vienna
10.22038/aojnmb.2019.35768.1242
Abstract
Objective(s): Prostate cancer (PC) is the most common cancer in men over 50 years of age. Bone scintigraphy is still performed in many institutions at the time of primary diagnosis. We aimed to evaluate the role of bone scan in the primary staging of PC in regard of different risk groups.
Methods: A retrospective analysis of bone scans in 296 patients (mean age 64±6 y) acquired at the time of primary diagnosis was performed in our institution. The median prostate specific antigen (PSA) was 6.73 ng/ml, all patients had a Gleason score of >5.
Results: Only 11/296 patients had a positive bone scan, 1 being in the intermediate risk group, 10 in the high-risk group and none in the low-risk group according to D’Amico classification.
Conclusion: Our results support the few published studies that less than 10% of patients with newly diagnosed PC by biopsy would develop bone metastasis, all in the intermediate or high-risk groups. Therefore, a staging by bone scan can only be recommended in patients with intermediate or high-risk, or symptomatic patients only.
Keywords
bone scintigraphy
prostate cancer
prostate specific antigen
PSA
Gleason Score
Subjects
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Asia Oceania Journal of Nuclear Medicine and Biology
Volume 7, Issue 2
July 2019
Pages 149-152