A case report of differentiated thyroid cancer presenting as a renal mass

Document Type : Case report

Authors

1 Karachi Institute of Radiotherapy & Nuclear Medicine, Karachi, Pakistan

2 Liaquat National Hospital, Stadium Road, Karachi, Pakistan

3 Sindh Institute of Urology & Transplant, Chand Bibi Road, Karachi, Pakistan

4 Gujranwala Institute of Nuclear Medicine & Radiotherapy, Nizampur, Gujranwala, Pakistan

Abstract

The kidney is an unconventional site for thyroid metastasis. As of the writing of this article, only about 30 cases have been reported. It presents like a renal mass. We are reporting a man with thyroid carcinoma presenting with distant metastasis to the kidney. He had complaints of abdominal pain and haematuria. Initial imaging suggested a left renal mass. A diagnosis of renal cell carcinoma was made and a nephrectomy was performed. Histopathology revealed it to be a metastasis from cancer of the thyroid gland. Subsequently, an ultrasound of the thyroid gland was performed, which showed a malignant appearing thyroid nodule. Correlative bone scan showed uptake at multiple skeletal sites. Total thyroidectomy was done and it was found to be papillary thyroid cancer. Subsequently, high dose radioactive iodine was administered. The patient was followed up and has recently found to have metastasis to the brain and is undergoing radiotherapy.

Keywords

References

  1. Prete A, de Souza PB, Censi S, Muzza M, Nucci N, Sponziello M. Update on fundamental mechanisms of thyroid cancer. Frontiers in endocrinology. 2020; 11:102.
  2. Liu Y, Su L, Xiao H. Review of Factors Related to the Thyroid Cancer Epidemic. International Journal of Endocrinology. 2017; 2017: 5308635.
  3. Li M, Dal Maso L, Vaccarella S. Global trends in thyroid cancer incidence and the impact of overdiagnosis. The Lancet Diabetes & Endocrinology. 2020; 8(6):468-70.
  4. Nguyen QT, Lee EJ, Huang MG, Park YI, Khullar A, Plodkowski RA. Diagnosis and treatment of patients with thyroid cancer. Am Health Drug Benefits. 2015; 8(1):30-40.
  5. Perros P, Boelaert K, Colley S, Evans C, Evans RM, Gerrard Ba G, et al. Guidelines for the management of thyroid cancer. Clinical endocrinology. 2014; 81:1-122.
  6. Yoon JH, Jeon MJ, Kim M, Hong AR, Kim HK, Shin DY, et al. Unusual metastases from differentiated thyroid cancers: A multicenter study in Korea. Plos one. 2020; 15(8):e0238207.
  7. Patel U, Ramachandran N, Halls J, Parthipun A, Slide C. Synchronous renal masses in patients with a nonrenal malignancy: incidence of metastasis to the kidney versus primary renal neoplasia and differentiating features on CT. American journal of roentgenology. 2011; 197(4):W680-W6.
  8. Falzarano SM, Chute DJ, Magi-Galluzzi C. Metastatic papillary thyroid carcinoma to the kidney: report of two cases mimicking primary renal cell carcinoma and review of the literature. Pathology-Journal of the RCPA. 2013; 45(1):89-93.
  9. Heitz P, Moser H, Staub JJ. Thyroid cancer. A study of 573 thyroid tumors and 161 autopsy cases observed over a thirty‐year period. Cancer. 1976; 37(5):2329-37.
  10. Gezer E, Selek A, Tarkun İ, Cantürk Z, Çetinarslan B. Papillary thyroid carcinoma presenting as a primary renal tumor with multiple pulmonary and bone metastases: a case report. Journal of medical case reports. 2019; 13(1):1-5.
Asia Oceania Journal of Nuclear Medicine and Biology
Volume 10, Issue 2
July 2022
Pages 147-150

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