We report a three-phase bone scintigraphy for the diagnosis of a peripheral bone lesion caused by systemic sarcoidosis. A 32-year-old man with suspected osteomyelitis of the right forefinger underwent three-phase bone scintigraphy with Tc-99m hydroxymethylene diphosphonate (HMDP) and single-photon emission computed tomography/computed tomography (SPECT/CT). The lesion was rich in blood flow according to flow study and blood pool study on bone scintigraphy, and was associated with an osteolytic change on SPECT/CT imaging performed 3 hours after injection of a radioisotope (RI). Whole-body bone scintigraphy indicated multiple high levels of abnormal RI accumulation. The findings of the three-phase bone scintigraphy and SPECT/CT suggested the presence of systemic sarcoidosis; however, a subsequent 18Ffluorodeoxyglucose positron emission tomography/CT (FDG-PET/CT) could not exclude the possibility of multiple metastases from testicular tumors. Therefore, testicular enucleation was performed, and the pathological examination confirmed the presence of sarcoidosis.
Higashiyama, S., Kawabe, J., Yoshida, A., Kotani, K., & Shiomi, S. (2014). Usefulness of three-phase bone scintigraphy and SPECT/CT for the diagnosis of bone lesions of systemic sarcoidosis. Asia Oceania Journal of Nuclear Medicine and Biology, 2(1), 69-72. doi: 10.7508/aojnmb.2014.01.010
MLA
Shigeaki Higashiyama; Joji Kawabe; Atsushi Yoshida; Kohei Kotani; Susumu Shiomi. "Usefulness of three-phase bone scintigraphy and SPECT/CT for the diagnosis of bone lesions of systemic sarcoidosis". Asia Oceania Journal of Nuclear Medicine and Biology, 2, 1, 2014, 69-72. doi: 10.7508/aojnmb.2014.01.010
HARVARD
Higashiyama, S., Kawabe, J., Yoshida, A., Kotani, K., Shiomi, S. (2014). 'Usefulness of three-phase bone scintigraphy and SPECT/CT for the diagnosis of bone lesions of systemic sarcoidosis', Asia Oceania Journal of Nuclear Medicine and Biology, 2(1), pp. 69-72. doi: 10.7508/aojnmb.2014.01.010
VANCOUVER
Higashiyama, S., Kawabe, J., Yoshida, A., Kotani, K., Shiomi, S. Usefulness of three-phase bone scintigraphy and SPECT/CT for the diagnosis of bone lesions of systemic sarcoidosis. Asia Oceania Journal of Nuclear Medicine and Biology, 2014; 2(1): 69-72. doi: 10.7508/aojnmb.2014.01.010