Asia Oceania Journal of Nuclear Medicine and Biology

Asia Oceania Journal of Nuclear Medicine and Biology

Extranodal involvement in lymphoma – A Pictorial Essay and Retrospective Analysis of 281 PET/CT studies

Document Type : Original Article

Authors
Jayanta Das 1
Soumendranath Ray 1
Saugata Sen 2
Mammen Chandy 3
1 Nuclear Medicine and PET/CT, Tata Medical Center, New Town, Kolkata, India
2 Radiology Department,Tata Medical Center, New Town, Kolkata, India
3 Haematology Department, Tata Medical Center, New Town, Kolkata, India
10.7508/aojnmb.2014.01.007
Abstract
Objective(s): The aim of this study is to evaluate the role of PET-CT in identification of different patterns of extranodal involvement in Hodgkin’s disease (HD) and Non-Hodgkin’s Lymphoma (NHL) and to enlist the common sites of extranodal involvement in each histological type and compare our results with the existing literature.
Methods: In this retrospective study of 281 cases of lymphomas of various histologies, we illustrate the spectrum of PET/CT features of extranodal lymphoma (ENL) of commonly involved organs and compare our result with the literature. Result: Extranodal appearance in lymphoma is strikingly varied. Diffuse large B cell lymphoma (DLBCL) is the commonest histological subtype and gastrointestinal tract is the commonest anatomical subsite in NHL. Skeletal system is the commonest site for involvement in HD.
Conclusion: A broad spectrum of extranodal organs is involved in various subtype of lymphoma which can be depicted in PET-CT in the most appropriate manner. Familiarity with the pattern of involvement is essential for comprehensive management.
Keywords
Hodgkin's disease
Lymphoma
PET/CT
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