Asia Oceania Journal of Nuclear Medicine and Biology

Asia Oceania Journal of Nuclear Medicine and Biology

18F-FDG PET CT in cardiac device infections - A Case series

Document Type : Case Series

Authors
Awiral Saxena
Manjit Sarma
Bhagirath Bhad
Ramkesh Ratheesan
Padma Subramanyam
P. Shanmuga Sundaram
Department of Nuclear Medicine & Molecular Imaging, Amrita Institute of Medical Science, Kochi, Kerala, India
10.22038/aojnmb.2024.77504.1547
Abstract
With the increasing number of interventional cardiology procedures, the number of cardiac device infections (including pacemakers, prosthetic valves, coronary and aortic stents) have also increased. These infections can cause significant morbidity and can even lead to mortality if not managed promptly. If suspected clinically the first-line imaging modality is Trans-Thoracic Echocardiography, while Transesophageal Echocardiography is also used in selected cases. The confirmation of a cardiac device infection is mostly done with the help of blood or pus culture. Even though Echocardiography is a very efficient technique for the evaluation of the heart, it cannot differentiate infection from thrombus or fibrosis. With the increasing availability of Positron Emission Tomography CT (PET CT) machines worldwide, the use of 18F-FDG PET CT for infection imaging has gained traction, especially for cardiac device infection. Most of the recent studies show a good diagnostic accuracy of 18F-FDG PET CT with many of the recent diagnostic and management guidelines now acknowledging its role, especially in equivocal cases. We present six such cases where 18F-FDG PET CT provided valuable information either for diagnosis, confirming the presence of infection, delineating extent, therapy response or sometimes even helping appropriate treatment decision making in patients with suspected cardiac device infection.
Keywords
18-F FDG PET CT
Coronary Stent infection
Prosthetic valve infection
CIED infection
Infection imaging
Subjects
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Asia Oceania Journal of Nuclear Medicine and Biology
Volume 12, Issue 2
July 2024
Pages 161-169