Asia Oceania Journal of Nuclear Medicine and Biology

Asia Oceania Journal of Nuclear Medicine and Biology

Utility of FDG PET/CT in Sjögren’s Syndrome and associated lymphomas; Lymphomagenesis

Document Type : Review article

Authors
Dikhra Khan 1
Prateek Kaushik 1
Sambit Sagar 1
Jasim Jaleel 2
1 India Department Of Nuclear Medicine All India Institute of Medical Sciences, Delhi, India
2 Assistant Professor,Department of Nuclear Medicine,, Institute of Liver and Biliary Sciences, New Delhi, Delhi, India.
10.22038/aojnmb.2024.76893.1541
Abstract
Primary Sjögren syndrome (SS) is an autoimmune disease affecting exocrine glands, with predisposition to development of lymphoma (lymphomagenesis). We report a case of Sjogren’s syndrome and discuss the role of FDG PET/CT in the primary diagnosis of lymphoma transformation in SS. Furthermore, we reviewed the literature regarding the utility of FDG PET/CT to assess systemic disease activity and also its role in the SS associated lymphoma with light into the new PET tracers that can be explored for these indications in the future.  Published data suggest promising role of FDG PET/CT in SS associated lymphomas, and demands larger studies for its establishment.
Keywords
Primary Sjögren syndrome
Lymphoma
Lymphomagenesis
FDG
PET/CT
Subjects
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Asia Oceania Journal of Nuclear Medicine and Biology
Volume 13, Issue 1
January 2025
Pages 102-106