Asia Oceania Journal of Nuclear Medicine and Biology

Asia Oceania Journal of Nuclear Medicine and Biology

Focal radiotracer uptake in the falciform ligament; A rare lymphoscintigraphic pattern in breast cancer

Document Type : Case report

Authors
Amin Saber Tanha
Farid Jafari Zarrin Ghabaei
Pegah Sahafi
Mohammad Ahmadi
Ramin Sadeghi
Nuclear Medicine Research Center, Mashhad university of Medical Sciences, Mashhad, Iran
10.22038/aojnmb.2024.80086.1564
Abstract
Breast cancer lymphoscintigraphy is a crucial tool in pre-operative assessment, typically revealing sentinel lymph node drainage patterns within axillary and extra-axillary regions. However, rare cases challenge conventional understanding. We report a 67-year-old woman with breast cancer, where lymphoscintigraphy revealed focal uptake within the falciform ligament of the liver, an exceedingly rare phenomenon. Clinical examination and imaging showed no axillary lymph node involvement. Lymphoscintigraphy and subsequent Single-photon emission computed tomography (SPECT)/computed tomography (CT) uncovered two axillary lymph nodes and an atypical focal uptake in the falciform ligament. Histopathology revealed no metastasis in sentinel nodes. The conventional understanding of breast lymphatic drainage primarily involves axillary and extra-axillary pathways, with the falciform ligament rarely implicated. This case suggests a unique lymphatic pathway connecting the breast and liver, possibly influencing metastasis. Factors such as lymphatic obstruction and valvular incompetency may contribute. This case highlights the importance of comprehensive lymphatic mapping in breast cancer evaluation and underscores the need for further research into atypical lymphatic pathways.
Keywords
Breast Lymphoscintigraphy
Falciform Ligament
Breast Cancer
Subjects
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Asia Oceania Journal of Nuclear Medicine and Biology
Volume 13, Issue 1
January 2025
Pages 114-116